Excessive weight gain after remission of depression in a schizophrenic patient treated with risperidone: case report
2006

Weight Gain After Depression in a Schizophrenic Patient on Risperidone

Sample size: 1 publication Evidence: low

Author Information

Author(s): Christos G Theleritis, George N Papadimitriou, Charalabos C Papageorgiou, Dimitris G Dikeos, Vasilis Masdrakis, Constantin Kostoulas, Constantin Psarros, Constantin R Soldatos

Primary Institution: Department of Psychiatry, Athens University Medical School, Eginition Hospital

Hypothesis

Is there an association between the remission of depression and excessive weight gain in a schizophrenic patient treated with risperidone?

Conclusion

The case suggests a probable association between the remission of depressive symptomatology and weight gain in a schizophrenic patient.

Supporting Evidence

  • The patient gained 52 kg after the remission of depression.
  • Re-administration of fluoxetine did not reverse the weight gain.
  • The patient developed diabetes mellitus, which was controlled with metformin.

Takeaway

A woman with schizophrenia gained a lot of weight after her depression got better while taking medication. Even when she tried to lose weight, it was hard for her.

Methodology

Case report detailing the patient's treatment and weight changes over four years.

Limitations

The findings are based on a single case and may not be generalizable.

Participant Demographics

Caucasian 33-year-old married female.

Digital Object Identifier (DOI)

10.1186/1471-244X-6-37

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