Prognostic utility of human complement factor H related protein test (the BTA stat® Test)
2001

Prognostic Utility of the BTA stat Test for Bladder Cancer

Sample size: 116 publication Evidence: moderate

Author Information

Author(s): M-P Raitanen, E Kaasinen, E Rintala, E Hansson, P Nieminen, R Aine, T L J Tammela

Primary Institution: Tampere University Hospital

Hypothesis

The study aims to determine the correlation of the BTA stat Test with disease-free interval in primary superficial bladder cancer, alongside traditional prognostic factors.

Conclusion

The BTA stat Test is sensitive in detecting primary bladder cancer and may provide independent prognostic information.

Supporting Evidence

  • 73 out of 97 patients with a positive BTA stat Test had a higher risk of recurrence.
  • Cytology detected only 20.6% of cases compared to the BTA stat Test.
  • The DFI was shorter for patients with positive BTA stat Test results.

Takeaway

This study looked at a test that helps predict how likely bladder cancer is to come back after treatment, finding that a positive test means a higher chance of recurrence.

Methodology

A prospective multicentre study evaluating 116 patients with newly diagnosed bladder cancer using the BTA stat Test, cytology, and follow-up data analysis.

Limitations

The study did not find significant relationships between tumour size and disease-free interval, nor between the number of tumours and DFI.

Participant Demographics

Patients with newly diagnosed bladder cancer, with 83.6% eligible for analysis.

Statistical Information

P-Value

0.041

Statistical Significance

p=0.041

Digital Object Identifier (DOI)

10.1054/bjoc.2001.1938

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