Active Bacterial Core Surveillance: A Progress Report
2001

Surveillance of Bacterial Infections in the U.S.

Sample size: 6992 publication Evidence: high

Author Information

Author(s): Anne Schuchat, Tami Hilger, Elizabeth Zell, Monica M. Farley, Arthur Reingold, Lee Harrison, Lewis Lefkowitz, Richard Danila, Karen Stefonek, Nancy Barrett, Dale Morse, Robert Pinner

Primary Institution: Centers for Disease Control and Prevention

Hypothesis

What is the burden of community-acquired invasive bacterial infections in the U.S.?

Conclusion

The Active Bacterial Core surveillance program estimates nearly 100,000 invasive infections and 10,000 deaths annually due to specific bacterial pathogens in the U.S.

Supporting Evidence

  • ABCs reported 6,992 cases of invasive disease caused by five pathogens in 1998.
  • Incidence rates of invasive disease ranged from 1.0 for N. meningitidis to 24.1 for S. pneumoniae.
  • Approximately 25% of invasive pneumococcal infections were not susceptible to penicillin.
  • Early-onset group B streptococcal disease declined by 65% over six years.

Takeaway

This study shows that many people get very sick from certain bacteria every year, and some of them die, even though we have medicines to help.

Methodology

The study used population-based active surveillance to collect data on invasive bacterial infections across multiple states.

Limitations

The study may not capture all cases as not all states routinely collect data on these infections.

Participant Demographics

The surveillance covered a population of 17 to 30 million across multiple states.

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