Proteomic Profile of Dormant Trichophyton Rubrum Conidia
Author Information
Author(s): Leng Wenchuan, Liu Tao, Li Rui, Yang Jian, Wei Candong, Zhang Wenliang, Jin Qi
Primary Institution: State Key Laboratory for Molecular Virology and Genetic Engineering, Institute of Pathogen Biology, Chinese Academy of Medical Sciences, Beijing, PR China
Hypothesis
We hypothesize that these spore specific proteins are related to the survival and dispersal of T. rubrum conidia.
Conclusion
The proteome of T. rubrum conidia is complex, indicating that maintaining conidial dormancy is an intricate process.
Supporting Evidence
- 1026 proteins were identified in the proteome analysis of dormant T. rubrum conidia.
- Functional classification revealed that the identified proteins covered nearly all major biological processes.
- Some proteins were spore specific and related to the survival and dispersal of T. rubrum conidia.
Takeaway
This study looks at the proteins in dormant T. rubrum conidia, which are important for their survival and ability to cause infections.
Methodology
Shotgun proteomics combined with sample prefractionation and multiple enzyme digestion was used to analyze the proteome.
Limitations
The study could not determine which identified proteins belong to hyphal fragments due to a lack of quantitative information.
Digital Object Identifier (DOI)
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