A case-control study of mastitis: nasal carriage of Staphylococcus aureus
2006

Study on Mastitis and Staphylococcus aureus in Breastfeeding Women

Sample size: 199 publication 10 minutes Evidence: moderate

Author Information

Author(s): Amir Lisa H, Garland Suzanne M, Lumley Judith

Primary Institution: La Trobe University

Hypothesis

Is maternal nasal carriage of Staphylococcus aureus associated with mastitis in breastfeeding women?

Conclusion

Maternal nasal carriage of S. aureus is not associated with mastitis, but infant nasal carriage is linked to breast infections.

Supporting Evidence

  • Infants of mothers with mastitis had a higher rate of nasal carriage of S. aureus (82%) compared to controls (56%).
  • There was a strong association between nipple damage and mastitis (adjusted OR 9.34).
  • The study found no significant difference in nasal carriage of S. aureus between mothers with and without mastitis.

Takeaway

The study looked at whether mothers carrying a germ called S. aureus in their noses could cause breast infections while breastfeeding. It found that while mothers didn't carry it more than others, their babies often did, which could lead to infections.

Methodology

A case-control study design was used, recruiting 100 women with mastitis and 99 breastfeeding controls, with questionnaires and nasal specimens collected.

Potential Biases

The control group was more likely to be from higher income brackets due to recruitment methods, which may affect results.

Limitations

The study relied on clinical signs for mastitis diagnosis and had potential selection bias in control recruitment.

Participant Demographics

Women with mastitis were older (mean age 34) and had lower family income compared to controls.

Statistical Information

P-Value

p<0.05

Confidence Interval

95% CI 1.30, 8.27

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1186/1471-2296-7-57

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