The contribution of dental amalgam to urinary mercury excretion in children
2008

Urinary Mercury Levels in Children with Amalgam Fillings

Sample size: 289 publication Evidence: moderate

Author Information

Author(s): Guzzi Gianpaolo, Pigatto Paolo D.

Primary Institution: Italian Association for Metals and Biocompatibility Research

Hypothesis

Does exposure to dental amalgam fillings affect urinary mercury excretion in children?

Conclusion

Children with dental amalgam fillings may have increased urinary mercury levels, but this does not necessarily reflect tissue retention of mercury.

Supporting Evidence

  • Urinary mercury concentrations are widely used as a measure of mercury exposure from dental amalgam fillings.
  • Previous studies have shown that urinary mercury is a rough indicator of mercury from dental amalgams.
  • Findings suggest that kidneys are the major contributors of urinary mercury.

Takeaway

This study looks at how dental fillings can affect the amount of mercury in children's urine, but just because there's mercury in the urine doesn't mean it's harmful.

Methodology

The study evaluated urinary mercury excretion in children with dental amalgam fillings.

Potential Biases

Potential bias in interpreting urinary mercury as a reliable indicator of mercury exposure.

Limitations

The study did not consider bruxism as a confounding factor affecting mercury levels.

Participant Demographics

289 adults, with 75.09% women and a median age of 43.

Digital Object Identifier (DOI)

10.1289/ehp.11235

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