Anal carcinoma in inflammatory bowel disease
2000
Anal Cancer in Inflammatory Bowel Disease
Sample size: 9602
publication
Evidence: moderate
Author Information
Author(s): Frisch M, Johansen C
Primary Institution: Danish Epidemiology Science Centre, Statens Serum Institut
Hypothesis
Does inflammatory bowel disease increase the risk of anal squamous cell carcinoma?
Conclusion
Anal squamous cell carcinoma is rare even in patients with inflammatory bowel disease.
Supporting Evidence
- 9602 patients with Crohn's disease or ulcerative colitis were followed.
- Only two cases of anal squamous cell carcinoma were observed.
- 1.3 cases were expected during the observation period.
Takeaway
This study looked at a lot of people with bowel diseases to see if they get anal cancer more often, and it turns out they don't.
Methodology
Followed patients with Crohn's disease or ulcerative colitis for anal squamous cell carcinoma over up to 18 years.
Participant Demographics
Patients with Crohn's disease or ulcerative colitis.
Statistical Information
Confidence Interval
0.2–5.7
Digital Object Identifier (DOI)
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