Antidiabetic Effects of Grape Skin Extracts from Croatian Varieties
Author Information
Author(s): Rastija Vesna, Drenjančević Mato, Kujundžić Toni, Zmaić Luka, Karnaš Maja
Primary Institution: Faculty of Agrobiotechnical Sciences Osijek, Josip Juraj Strossmayer University of Osijek
Hypothesis
This study aimed to determine and compare the antidiabetic potential of grape skin from indigenous Croatian white grapevine varieties.
Conclusion
The study found that grape skin extracts from indigenous Croatian varieties have significant antidiabetic potential, particularly the 'Svetokriška belina' variety.
Supporting Evidence
- The 'Svetokriška belina' variety had the highest total phenolic content and antioxidant activity.
- The grape skin extracts showed significant inhibition of α-amylase and α-glucosidase.
- Principal component analysis revealed relationships among grape varieties based on their inhibition potential.
Takeaway
Grape skins from certain Croatian grapes can help lower blood sugar, which is good for people with diabetes.
Methodology
The study involved extracting grape skins, measuring total phenols, antioxidant activity, and testing inhibition of α-amylase and α-glucosidase enzymes.
Limitations
The study focused only on a limited number of grape varieties and did not explore the long-term effects of the extracts.
Statistical Information
P-Value
0.007
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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