Comparative analysis of differentially expressed genes in normal and white spot syndrome virus infected Penaeus monodon
2007

Gene Expression Changes in Shrimp Infected with White Spot Syndrome Virus

Sample size: 50 publication 10 minutes Evidence: high

Author Information

Author(s): Leu Jiann-Horng, Chang Chih-Chin, Wu Jin-Lu, Hsu Chun-Wei, Hirono Ikuo, Aoki Takashi, Juan Hsueh-Fen, Lo Chu-Fang, Kou Guang-Hsiung, Huang Hsuan-Cheng

Primary Institution: Institute of Zoology, National Taiwan University

Hypothesis

This study aims to identify the molecular mechanisms of gene expression changes in Penaeus monodon postlarvae infected with white spot syndrome virus (WSSV).

Conclusion

WSSV infection modulates the expression of various genes in shrimp, affecting their physiological functions and cellular processes.

Supporting Evidence

  • WSSV infection leads to significant changes in gene expression patterns in shrimp.
  • High-quality ESTs were generated from both normal and infected shrimp libraries.
  • Gene Ontology analysis revealed significant differences in biological processes affected by WSSV.

Takeaway

When shrimp get sick from a virus, their bodies change how they use genes, which can help scientists understand how to protect them.

Methodology

The study used expressed sequence tags (ESTs) to analyze gene expression in shrimp postlarvae before and after WSSV infection.

Limitations

The study primarily focused on gene expression without exploring the functional implications of the identified genes.

Participant Demographics

The study involved postlarvae of Penaeus monodon, specifically at the PL20 stage.

Statistical Information

P-Value

<0.001

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1186/1471-2164-8-120

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