Prognostic Factors for Cancer Survival in Follicular Thyroid Carcinoma
Author Information
Author(s): Buzejic Matija, Bukumiric Zoran, Rovcanin Branislav, Jovanovic Milan, Stojanovic Marina, Zoric Goran, Tausanovic Katarina, Slijepcevic Nikola, Zivaljevic Vladan
Primary Institution: University Clinical Center of Serbia
Hypothesis
What are the prognostic factors affecting cancer-specific survival and disease-free interval in patients with follicular thyroid carcinoma?
Conclusion
The study found that the 10-year survival rate for patients with follicular thyroid carcinoma is relatively favorable, but certain factors like distant metastases and tumor type can negatively impact prognosis.
Supporting Evidence
- Distant metastases occurred in 12 patients during the follow-up period.
- The 5-year cancer-specific survival rate was 98.1%.
- Independent unfavorable prognostic factors for cancer-specific survival included widely invasive tumor type and multifocality.
Takeaway
This study looked at patients with a type of thyroid cancer and found that some things, like having multiple tumors or cancer that spreads, can make it harder for them to survive.
Methodology
A retrospective cohort study analyzing clinical data from 130 patients with follicular thyroid carcinoma who underwent surgery between 1995 and 2020.
Potential Biases
Potential bias from including patients with mixed tumor types in previous studies.
Limitations
The study's long time frame may influence results due to advancements in technology, and some distant metastases may not have been detected.
Participant Demographics
Mean age of patients was 51.4 years, with a female to male ratio of 3:1.
Statistical Information
Confidence Interval
95% CI 1.29–10.18 for tumor type, 95% CI 1.37–32.72 for multifocality, and 95% CI 1.08–4.84 for distant metastases.
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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