Is membranous location of EGFR or EGFRvIII immunostaining associated with good prognosis in renal cell carcinoma?
2005
EGFR Immunostaining and Prognosis in Renal Cell Carcinoma
publication
Author Information
Author(s): Modjtahedi H, Cunningham M P
Primary Institution: University of Surrey
Hypothesis
Is membranous location of EGFR or EGFRvIII immunostaining associated with good prognosis in renal cell carcinoma?
Conclusion
Membranous EGFR expression is associated with longer overall survival in renal cell carcinoma patients.
Supporting Evidence
- Membranous EGFR expression is linked to better survival outcomes in RCC patients.
- Previous studies have shown conflicting results regarding EGFR expression and prognosis.
Takeaway
If a cancer has a lot of a certain protein on its surface, it might mean the patient will live longer.
Limitations
The authors need to clarify conflicting statements in their methods regarding the use of antibodies.
Statistical Information
P-Value
0.004
Statistical Significance
p=0.004
Digital Object Identifier (DOI)
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