Rabies Surveillance in Madagascar (2005-2010)
Author Information
Author(s): Reynes Jean-Marc, Andriamandimby Soa Fy, Razafitrimo Girard Marcelin, Razainirina Josette, Jeanmaire Elisabeth Marie, Bourhy Hervé, Heraud Jean-Michel
Primary Institution: Institut Pasteur de Madagascar
Hypothesis
To assess the circulation of lyssavirus in Madagascar from 2005 to 2010.
Conclusion
Rabies remains endemic in Madagascar despite the introduction of the vaccine over a century ago.
Supporting Evidence
- Half of the 437 domestic or tame wild terrestrial mammal brains tested were found RABV antigen positive.
- Nine of the 10 suspected human cases tested were laboratory confirmed.
- RABV circulation was confirmed in 34 of the 38 districts sampled.
Takeaway
This study looked at rabies in Madagascar and found that even with vaccines, the disease is still common, especially in dogs.
Methodology
Animal and human samples were tested for rabies virus using various detection methods including antigen detection and virus isolation.
Limitations
The study was limited by the number of samples from certain districts and the inadequate storage of some samples.
Participant Demographics
Samples included 450 from animals (mostly dogs and cats) and 11 from humans.
Statistical Information
Confidence Interval
95% CI 53.6%–67.7%
Digital Object Identifier (DOI)
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