1-[(Butylamino)(phenyl)methyl]naphthalen-2-ol
2011
Synthesis and Crystal Structure of a New Compound
publication
Evidence: moderate
Author Information
Author(s): Ni Hen-Mei
Primary Institution: Southeast University
Hypothesis
The study investigates the synthesis and crystal structure of a compound derived from a Betti-type reaction.
Conclusion
The compound exhibits a stable molecular conformation due to an intramolecular hydrogen bond.
Supporting Evidence
- The compound was synthesized using a one-pot reaction.
- An intramolecular O—H⋯N hydrogen bond stabilizes the molecular conformation.
- The dihedral angle between the fused ring system and the phenyl ring is 78.27°.
Takeaway
Scientists made a new chemical compound and found that its structure is held together by special bonds, making it stable.
Methodology
The compound was synthesized through a three-component condensation reaction without solvent, followed by crystallization.
Digital Object Identifier (DOI)
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