Nanogold in Denture Bases Reduces Microbial Growth
Author Information
Author(s): Zidan Yasmin S., Abdel-Hamid Reham H., Elshiekh Reham M., El Gohary Sara M.
Primary Institution: Al-Azhar University, Cairo, Egypt
Hypothesis
Does the incorporation of nanogold particles into PMMA denture bases reduce microbial activity in implant-retained mandibular overdentures?
Conclusion
The addition of gold nanoparticles to PMMA denture bases was more effective in inhibiting microbial growth than conventional acrylic resin bases.
Supporting Evidence
- Group II had significantly lower microbial counts than Group I at all time points.
- The study showed a significant reduction in Candida albicans, E. coli, and S. mutans in the nanogold group.
- Gold nanoparticles are known for their antibacterial properties.
Takeaway
Adding tiny gold particles to dentures helps keep them cleaner by stopping germs from growing.
Methodology
This randomized clinical trial involved 22 male patients divided into two groups, comparing conventional PMMA denture bases with those modified with nanogold.
Limitations
The study's findings may be influenced by factors such as the duration of denture use and oral hygiene practices.
Participant Demographics
Male patients aged 50 to 60, completely edentulous.
Statistical Information
P-Value
p<0.001
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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