Complementary and alternative medicine use among women at increased genetic risk of breast and ovarian cancer
2008

Use of Complementary and Alternative Medicine Among Women at Genetic Risk for Breast and Ovarian Cancer

Sample size: 164 publication Evidence: moderate

Author Information

Author(s): Christine M. Mueller, Phuong L. Mai, Jaime Bucher, June A. Peters, Jennifer T. Loud, Mark H. Greene

Primary Institution: National Cancer Institute, National Institutes of Health

Hypothesis

What are the rates and patterns of complementary and alternative medicine (CAM) use among women at increased genetic risk of breast cancer?

Conclusion

The study found that 78% of BRCA mutation carriers reported using CAM, indicating a high prevalence comparable to breast cancer patients and survivors.

Supporting Evidence

  • 78% of BRCA+ women reported using CAM.
  • 34% of participants used three or more CAM therapies.
  • Older age, higher education, and previous cancer diagnosis were associated with increased CAM use.

Takeaway

Many women who are at risk for breast cancer use alternative treatments to help them feel better, just like women who have had breast cancer.

Methodology

Participants completed a pre-visit telephone interview about their CAM use and were evaluated using logistic regression to assess associations with various factors.

Potential Biases

The sample may not be representative of all BRCA mutation carriers as it consisted mainly of highly-educated white women.

Limitations

The study relied on self-reported data, lacked detailed information on the frequency and duration of CAM use, and had a relatively small sample size.

Participant Demographics

Participants were predominantly white (97.6%), highly educated (92.7% attended college), and mostly married (72%).

Statistical Information

P-Value

0.006

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1186/1472-6882-8-17

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