Hemolytic Disease of the Fetus and Newborn: Current Trends and Perspectives
Author Information
Author(s): Basu Sabita, Kaur Ravneet, Kaur Gagandeep
Primary Institution: Government Medical College and Hospital, Chandigarh, India
Hypothesis
Universal antenatal screening in all pregnant women is necessary to detect alloantibodies.
Conclusion
The spectrum of hemolytic disease of the fetus and newborn has shifted, with ABO incompatibility and other alloantibodies now being major causes.
Supporting Evidence
- ABO incompatibility is now the single largest cause of hemolytic disease of the newborn in the western world.
- Many developed nations have implemented regular screening of all pregnant women.
- Reports from Asian countries indicate severe hemolytic disease due to alloantibodies other than anti D.
Takeaway
Doctors need to check all pregnant women for certain antibodies to help prevent serious problems for babies.
Methodology
Review of current trends and practices in antenatal screening and management of hemolytic disease.
Limitations
The cost and infrastructure required for universal screening in developing countries are significant.
Participant Demographics
Focus on pregnant women, particularly in developing countries and Asian populations.
Digital Object Identifier (DOI)
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