Predicting Early Death in Elderly Patients with Laryngeal Cancer
Author Information
Author(s): Liang Qi-Wei, Gao Xi-Lin, Zhang Jun-wei
Primary Institution: The Ninth People’s Hospital of Shenzhen, Shenzhen, China
Hypothesis
This study aimed to identify risk factors associated with early death in elderly patients with laryngeal squamous cell carcinoma and to establish predictive nomograms.
Conclusion
The study provides nomograms that help predict early mortality in elderly patients with laryngeal squamous cell carcinoma, aiding in personalized treatment plans.
Supporting Evidence
- 1,711 out of 10,031 patients experienced all-cause early death.
- Patients with advanced T and N stages had a higher risk of early mortality.
- Nomograms showed an area under the curve of 0.796 for all-cause death prediction.
Takeaway
Doctors can use special charts to figure out which older patients with throat cancer are more likely to die soon, so they can give them better care.
Methodology
Data from the SEER database was analyzed using logistic regression models to identify risk factors for early death and to create predictive nomograms.
Potential Biases
Selection bias may be present due to the retrospective nature of the study.
Limitations
The study lacks information on smoking, alcohol consumption, and comorbidities, and it is based on retrospective data, which may introduce selection bias.
Participant Demographics
Most participants were elderly (≥60 years), predominantly white (83.1%), and male (80.8%).
Statistical Information
P-Value
p<0.001
Confidence Interval
CI 1.49–2.18
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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