High-Dose Dobutamine Stress MRI at 3 Tesla
Author Information
Author(s): Kelle S, Hamdan A, Schnackenburg B, Köhler U, Klein C, Nagel E, Fleck E
Primary Institution: Deutsches Herzzentrum Berlin
Hypothesis
High-dose DCMR in combination with contrast agent administration at 3 Tesla is feasible to detect significant coronary stenoses in patients with suspected or known CAD.
Conclusion
High-dose DCMR at 3T is feasible and an accurate method to depict significant coronary artery stenosis in patients with suspected or known CAD.
Supporting Evidence
- DCMR was performed successfully in 27 out of 30 patients.
- Coronary angiography showed significant stenosis in 68.2% of patients.
- Patient-based sensitivity and specificity were 80.0% and 85.7%, respectively.
Takeaway
Doctors used a special MRI test to see if patients had serious heart problems, and it worked well with a stronger machine.
Methodology
Thirty patients underwent DCMR at 3 Tesla to assess coronary artery disease using a standardized dobutamine-atropine protocol.
Limitations
The study had a small sample size and was conducted at a single center, limiting generalizability.
Participant Demographics
30 patients (24 men, 6 women; mean age 66 ± 9.3 years) with suspected or known coronary artery disease.
Statistical Information
P-Value
p<0.0001
Statistical Significance
p<0.0001
Digital Object Identifier (DOI)
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