Impact of shock index (SI), modified SI, and age-derivative indices on acute heart failure prognosis; A systematic review and meta-analysis
2024

Impact of Shock Index on Acute Heart Failure Prognosis

Sample size: 12955 publication 10 minutes Evidence: moderate

Author Information

Author(s): Vakhshoori Mehrbod, Bondariyan Niloofar, Sabouhi Sadeq, Shakarami Mehrnaz, Emami Sayed Ali, Nemati Sepehr, Tavakol Golchehreh, Yavari Behzad, Shafie Davood

Primary Institution: Heart Failure Research Center, Isfahan Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran

Hypothesis

The study aims to evaluate the effect of shock index and its derivatives on acute heart failure clinical outcomes.

Conclusion

Shock index, age shock index, and modified shock index are practical tools for assessing prognosis in acute heart failure patients.

Supporting Evidence

  • Mean shock index in those records reported mortality was 0.67.
  • In-hospital mortality rate was 6.18% among 12955 patients.
  • Deceased patients had higher shock index values compared to survivors.
  • Shock index was associated with higher odds of in-hospital death (OR: 1.93).
  • Optimal shock index cut-off point was found to be 0.79.

Takeaway

Doctors can use simple calculations like the shock index to help figure out how serious a heart failure patient is and how likely they are to get better.

Methodology

The study conducted a systematic review and meta-analysis of relevant records from PubMed/Medline, Scopus, and Web of Science databases.

Potential Biases

Potential biases in data collection and analysis due to the retrospective nature of most studies.

Limitations

Considerable heterogeneity among studies and potential biases due to retrospective designs.

Participant Demographics

Mean age of participants was 69.44 years, with a majority being male.

Statistical Information

P-Value

0.012

Confidence Interval

95% CI: 0.63–0.73

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1371/journal.pone.0314528

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