Serpentine Supravenous Hyperpigmentation from Chemotherapy
Author Information
Author(s): Hanieh Radkhah, Saba Maleki, Razman Arabzadeh Bahri
Primary Institution: Tehran University of Medical Sciences
Hypothesis
The study aims to systematically review the serpentine supravenous dermatitis induced by chemotherapeutic agents.
Conclusion
SSH is a dermatologic reaction that mostly occurs with peripheral venous access for chemotherapy injections and typically improves spontaneously.
Supporting Evidence
- SSH is a self-limiting condition that resolves after stopping chemotherapy.
- Docetaxel was the most commonly reported chemotherapeutic agent associated with SSH.
- Most skin lesions were self-limiting with normal histopathological findings.
Takeaway
When people get chemotherapy, sometimes their skin can change color in a snake-like pattern near where the medicine goes in, but it usually goes away on its own.
Methodology
A systematic review was conducted by searching databases like Scopus and PubMed for studies on SSH in cancer patients after chemotherapy.
Limitations
The review may not include all relevant studies due to the exclusion of non-cancer patients and those using medications other than chemotherapeutics.
Participant Demographics
The study included 26 patients (18 males and 8 females) with a mean age of 52.96 years.
Digital Object Identifier (DOI)
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