Home Administration of Lanreotide Autogel for Acromegaly
Author Information
Author(s): Bevan J S, Newell-Price J, Wass J A H, Atkin S L, Bouloux P M, Chapman J, Davis J R E, Howlett T A, Randeva H S, Stewart P M, Viswanath A
Hypothesis
Can patients with acromegaly successfully self-administer lanreotide Autogel injections at home without compromising efficacy or safety?
Conclusion
Patients with acromegaly or their partners can safely administer lanreotide Autogel injections at home without losing efficacy.
Supporting Evidence
- All Test group patients/partners qualified to administer injections.
- 14 of 15 Test group patients maintained growth hormone and IGF-1 control.
- Local injection tolerability was good for both treatment groups.
Takeaway
This study shows that people with acromegaly can give themselves their medicine at home, which is just as safe and effective as getting it from a doctor.
Methodology
Multicentre, open-label, nonrandomised, controlled study with 30 patients divided into Test and Control groups.
Potential Biases
Differences in baseline characteristics between groups due to non-randomization.
Limitations
Patients were not randomized to treatment, which may introduce bias.
Participant Demographics
30 patients aged 29-86 years, 43% female.
Statistical Information
P-Value
0.0001
Confidence Interval
95% CI 70–99%
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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