Aging Indicators and Premature Mortality Risk
Author Information
Author(s): Kou Minghao, Ma Hao, Wang Xuan, Qi Lu
Primary Institution: Tulane University
Hypothesis
The study investigates the association between visible and self-perceived aging indicators and the risk of premature mortality.
Conclusion
The combination of visible and self-perceived aging indicators is linked to a higher risk of all-cause and cause-specific premature mortality.
Supporting Evidence
- Participants with all aging indicators had an 81% higher risk of all-cause mortality.
- Those with aging indicators had a 96% higher risk of cardiovascular disease mortality.
- Participants with aging indicators experienced a 55% higher risk of cancer mortality.
- An additional 16.08% risk of premature mortality was associated with the frailty index.
Takeaway
If you look older or feel older, it might mean you're at a higher risk of dying young.
Methodology
The study used Cox proportional hazards models to analyze data from UK Biobank participants over a median follow-up of 13.74 years.
Participant Demographics
Participants were initially free of cardiovascular disease and cancer, with a follow-up until December 31, 2022.
Statistical Information
Confidence Interval
95% CI, 59%–107%
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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