Pyrethroid Resistance Reduces the Efficacy of Space Sprays for Dengue Control on the Island of Martinique (Caribbean)
2011

Impact of Pyrethroid Resistance on Dengue Control in Martinique

Sample size: 9 publication 10 minutes Evidence: high

Author Information

Author(s): Marcombe Sébastien, Darriet Frédéric, Tolosa Michel, Agnew Philip, Duchon Stéphane, Etienne Manuel, Yp Tcha Marie Michèle, Chandre Fabrice, Corbel Vincent, Yébakima André

Primary Institution: Institut de Recherche pour le Développement (IRD), Montpellier, France

Hypothesis

How does pyrethroid resistance affect the efficacy of space sprays for dengue control?

Conclusion

Pyrethroid resistance significantly reduces the effectiveness of space sprays in controlling dengue vector populations.

Supporting Evidence

  • High mortality rates were observed in susceptible mosquitoes treated with deltamethrin.
  • Resistant mosquitoes showed very low mortality rates.
  • No reduction in larval or adult mosquito populations was noted after treatments.

Takeaway

The study found that mosquitoes resistant to certain insecticides are harder to kill, making it tough to control dengue outbreaks.

Methodology

Field trials were conducted in 9 localities in Martinique to assess the efficacy of deltamethrin and natural pyrethrins against resistant Aedes aegypti populations.

Potential Biases

Potential bias in the selection of localities and the inherent variability in mosquito populations.

Limitations

The study was limited to specific localities and may not represent all areas affected by dengue.

Participant Demographics

The study focused on Aedes aegypti populations in Martinique.

Statistical Information

P-Value

<0.001

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1371/journal.pntd.0001202

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