Paleolithic Diet vs Cereal-Based Diet in Pigs
Author Information
Author(s): Jönsson Tommy, Ahrén Bo, Pacini Giovanni, Sundler Frank, Wierup Nils, Steen Stig, Sjöberg Trygve, Ugander Martin, Frostegård Johan, Göransson Leif, Lindeberg Staffan
Primary Institution: Lund University
Hypothesis
Does a Paleolithic diet improve insulin sensitivity and reduce risk factors for diseases of affluence compared to a cereal-based diet in domestic pigs?
Conclusion
A Paleolithic diet in domestic pigs leads to higher insulin sensitivity, lower C-reactive protein, and lower blood pressure compared to a cereal-based diet.
Supporting Evidence
- The Paleolithic group weighed 22% less than the cereal group.
- Dynamic insulin sensitivity was significantly higher in the Paleolithic group (p = 0.004).
- C-reactive protein levels were 82% lower in the Paleolithic group (p = 0.0007).
- Diastolic blood pressure was 13% lower in the Paleolithic group (p = 0.007).
- Insulin response was significantly lower in the Paleolithic group (p = 0.001).
Takeaway
Feeding pigs a Paleolithic diet makes them healthier by helping their bodies use insulin better and keeping their blood pressure lower.
Methodology
Twenty-four piglets were divided into two groups: one fed a Paleolithic diet and the other a cereal-based diet for 15 months, followed by glucose tolerance tests and various health measurements.
Potential Biases
Potential bias in dietary allocation and the effects of anesthesia on metabolic measurements.
Limitations
The study was limited by the small sample size and the specific animal model used, which may not fully represent human responses.
Participant Demographics
Cross-bred piglets from four different litters.
Statistical Information
P-Value
p = 0.001
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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