Neologistic Jargon Aphasia and Agraphia in Primary Progressive Aphasia
Author Information
Author(s): Jonathan D. Rohrer, Martin N. Rossor, Jason D. Warren
Primary Institution: Dementia Research Centre, Institute of Neurology, University College London, UK
Hypothesis
Involvement of the posterior superior temporal–inferior parietal region may lead to a disconnection between stored lexical representations and language output pathways, resulting in neologistic jargon.
Conclusion
The study describes two patients with primary progressive aphasia who developed neologistic jargon, suggesting that parietal lobe involvement may modify the language phenotype in neurodegenerative diseases.
Supporting Evidence
- Both patients exhibited neologistic jargon in the context of primary progressive aphasia.
- Neologisms are rarely reported in neurodegenerative diseases, making these cases noteworthy.
- Brain imaging showed asymmetrical atrophy in the left hemisphere, particularly affecting the temporal and parietal lobes.
Takeaway
This study looked at two people who had trouble speaking and writing because of brain problems, and they started making up new words that didn't make sense.
Methodology
The study involved detailed neuropsychological assessments and brain imaging of two patients with primary progressive aphasia.
Limitations
The study is based on only two case reports, limiting the generalizability of the findings.
Participant Demographics
Two right-handed patients, one female aged 75 and one male aged 70.
Digital Object Identifier (DOI)
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