Bioelectrical Impedance Phase Angle and Nutritional Assessment in Colorectal Cancer
Author Information
Author(s): Gupta Digant, Lis Christopher G, Dahlk Sadie L, King Jessica, Vashi Pankaj G, Grutsch James F, Lammersfeld Carolyn A
Primary Institution: Cancer Treatment Centers of America® (CTCA) at Midwestern Regional Medical Center
Hypothesis
The study investigates the association between bioelectrical impedance derived phase angle and subjective global assessment in advanced colorectal cancer.
Conclusion
Bioimpedance phase angle may serve as a potential nutritional indicator in advanced colorectal cancer.
Supporting Evidence
- Well-nourished patients had a higher median phase angle score compared to malnourished patients.
- The Spearman correlation coefficient between phase angle and SGA was 0.33.
- A phase angle cut-off of 5.9 showed high diagnostic accuracy in males who had failed primary treatment.
Takeaway
Doctors can use a special measurement called phase angle to help figure out if cancer patients are getting enough nutrition.
Methodology
A case series of 73 colorectal cancer patients was evaluated using bioelectrical impedance analysis and subjective global assessment.
Potential Biases
Potential bias due to the retrospective nature and reliance on existing data.
Limitations
The study's retrospective design and small sample size may limit the findings.
Participant Demographics
Patients included 41 males (50.6%) and 40 females (49.4%), with a mean age of 56 years.
Statistical Information
P-Value
0.004
Confidence Interval
95% CI = 0.57 to 0.82
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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