Effects of Aflatoxin B1 and Fumonisin B1 on Broiler Chickens
Author Information
Author(s): Tessari Eliana N. C., Kobashigawa Estela, Cardoso Ana Lúcia S. P., Ledoux David R., Rottinghaus George E., Oliveira Carlos A. F.
Primary Institution: Center for Advanced Technological Research on Poultry, Biological Institute, Brazil
Hypothesis
The study aims to evaluate the effects of dietary aflatoxin B1 and fumonisin B1 on liver pathology and blood biochemical parameters in broiler chickens.
Conclusion
The study found that aflatoxin B1 and fumonisin B1 can adversely affect liver function in broiler chickens, indicated by increased serum levels of AST and changes in plasma total protein levels.
Supporting Evidence
- Broilers fed higher levels of aflatoxin B1 and fumonisin B1 showed increased serum levels of aspartate amino-transferase (AST).
- Plasma total protein levels were significantly lower in groups fed 200 μg AFB1/kg alone or in combination with FB1.
- Histopathological examination revealed liver damage in broilers receiving the highest levels of AFB1 and FB1.
Takeaway
This study shows that certain toxins in chicken feed can hurt the chickens' livers and affect their health.
Methodology
The study used a completely randomized 3 x 3 factorial design with 108 broiler chicks assigned to different dietary treatments containing varying levels of aflatoxin B1 and fumonisin B1.
Limitations
The study did not measure serum alanine aminotransferase (ALT) levels, which are also important for assessing liver toxicity.
Participant Demographics
The participants were 1-day-old male broiler chicks from a commercial lineage.
Statistical Information
P-Value
p<0.05
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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