Prolonged response to first-line erlotinib for advanced lung adenocarcinoma
2008

Long-lasting response to erlotinib in lung cancer

publication Evidence: low

Author Information

Author(s): Michael Copeman

Primary Institution: Northern Beaches Cancer Service, Sydney, Australia

Hypothesis

Can erlotinib provide a prolonged response in patients with advanced lung adenocarcinoma who refuse chemotherapy?

Conclusion

Erlotinib can lead to significant radiological and symptomatic improvement in patients with advanced NSCLC who are unsuitable for chemotherapy.

Supporting Evidence

  • The patient had a partial response to erlotinib after 7 months.
  • Erlotinib was well tolerated with manageable side effects.
  • The patient maintained daily activities during treatment.

Takeaway

A woman with lung cancer felt better and had less pain after taking a medicine called erlotinib instead of chemotherapy.

Methodology

Case report detailing the patient's treatment and response to erlotinib.

Limitations

The findings are based on a single case report, limiting generalizability.

Participant Demographics

58-year-old non-smoking female of Philippine origin.

Statistical Information

Confidence Interval

95% confidence intervals 0.58–0.85

Digital Object Identifier (DOI)

10.1186/1756-9966-27-59

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