Long-Term Exposure to Traffic-Related Air Pollution and the Risk of Coronary Heart Disease Hospitalization and Mortality
2011

Traffic-Related Air Pollution and Heart Disease

Sample size: 452735 publication Evidence: high

Author Information

Author(s): Gan Wen Qi, Koehoorn Mieke, Davies Hugh W., Demers Paul A., Tamburic Lillian, Brauer Michael

Primary Institution: University of British Columbia

Hypothesis

Long-term exposure to traffic-related air pollutants is associated with increased risk of coronary heart disease morbidity and mortality.

Conclusion

Long-term exposure to traffic-related fine particulate air pollution, indicated by black carbon, may partly explain the observed associations between exposure to road traffic and adverse cardiovascular outcomes.

Supporting Evidence

  • An interquartile range elevation in black carbon was associated with a 3% increase in CHD hospitalization.
  • An interquartile range elevation in black carbon was associated with a 6% increase in CHD mortality.
  • CHD hospitalization and mortality rates were higher for individuals living in areas with higher neighborhood SES.

Takeaway

Living near busy roads can make your heart sick. Breathing in dirty air from cars can lead to heart problems.

Methodology

This population-based cohort study included a 5-year exposure period and a 4-year follow-up period, assessing individual exposures to traffic-related air pollutants and tracking CHD hospitalizations and deaths.

Potential Biases

Potential underestimation of true adverse effects due to unmeasured confounding factors and exposure misclassification.

Limitations

The study could not control for individual cardiovascular risk factors like smoking and relied on neighborhood socioeconomic status as a proxy for individual SES.

Participant Demographics

Participants were residents of Metropolitan Vancouver aged 45-85 years without known CHD at baseline.

Statistical Information

Confidence Interval

95% CI, 1–5% for hospitalization; 95% CI, 3–9% for mortality

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1289/ehp.1002511

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