4-(2,7-Dimethyl-4-oxo-1,3-thiazolo[4,5-d]pyridazin-5-yl)benzenesulfonamide
2011
Study of a New Compound with Antibacterial Properties
publication
Evidence: moderate
Author Information
Author(s): Asiri Abdullah M., Faidallah Hassan M., Ng Seik Weng
Primary Institution: King Abdul Aziz University
Hypothesis
The compound C13H12N4O3S2 will exhibit high antibacterial activity due to its unique chemical structure.
Conclusion
The study successfully synthesized a new compound that forms a dimer structure and shows potential antibacterial activity.
Supporting Evidence
- The compound has a thiazole–pyridazine fused-ring system that is approximately planar.
- The benzene ring is twisted by 39.3° relative to the fused-ring system.
- The amine group forms hydrogen bonds that create a dimer structure.
Takeaway
Scientists made a new chemical compound that might help fight bacteria. It has a special shape that helps it work better.
Methodology
The compound was synthesized by heating ethyl 5-acetyl-2-methylthiazole-4-carboxylate with p-sulfonamidophenyl hydrazine hydrochloride in ethanol.
Digital Object Identifier (DOI)
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