Exploring the Impact of Gender on the Characteristics and Complications of Eosinophilic Esophagitis
2024

Impact of Gender on Eosinophilic Esophagitis

Sample size: 21755 publication 10 minutes Evidence: moderate

Author Information

Author(s): Het Patel, Joshua Elmer, Liaquat Hammad

Primary Institution: St. Luke's University Healthcare Network

Hypothesis

Males are more prone to the complications of eosinophilic esophagitis due to greater disease severity.

Conclusion

Males have a higher rate of complications from eosinophilic esophagitis, while females are more prevalent in the Black population.

Supporting Evidence

  • Males had higher rates of esophageal obstruction and food bolus impaction.
  • Females with EoE were more likely to be from the Black population.
  • Esophageal impaction was more common in males ages 25–29.
  • Higher rates of complications were observed in males during the month of March.

Takeaway

Boys are more likely to have serious problems with a condition called eosinophilic esophagitis, while girls with this condition are often from the Black community.

Methodology

Retrospective cohort study using National Inpatient Sample data from 2016 to 2020.

Potential Biases

Potential selection bias due to the inclusion of only hospitalized patients.

Limitations

The study may not be applicable to all patients with eosinophilic esophagitis as it only includes those hospitalized.

Participant Demographics

52% male and 48% female, with a majority being White.

Statistical Information

P-Value

p<0.05

Confidence Interval

95% CI 1.063–1.429

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1002/jgh3.70059

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