Advanced Dynamic Centre of Pressure Diagnostics with Smart Insoles: Comparison of Diabetic and Healthy Persons for Diagnosing Diabetic Peripheral Neuropathy
2024

Smart Insoles for Diagnosing Diabetic Neuropathy

Sample size: 29 publication 10 minutes Evidence: high

Author Information

Author(s): Fuss Franz Konstantin, Tan Adin Ming, Weizman Yehuda

Primary Institution: University of Bayreuth

Hypothesis

The diabetes cohort diagnosed with peripheral neuropathy is less balanced than healthy volunteers.

Conclusion

Healthy volunteers and diabetic subjects have significantly different cyclogram geometries and balance index values, indicating potential for improved diagnostic classifiers for diabetic peripheral neuropathy.

Supporting Evidence

  • The balance index (BI) medians of the diabetes cohort and healthy cohort differed significantly.
  • Two distances and their ratio had an AUC > 0.94, indicating high potential as classifiers for diagnosing diabetic peripheral neuropathy.
  • The study found that the BI captures balance issues related to diabetic peripheral neuropathy.

Takeaway

This study used smart insoles to measure how people with diabetes walk compared to healthy people, finding that those with diabetes often have balance issues.

Methodology

Participants walked on a flat walkway while wearing smart insoles that measured their center of pressure, and various parameters were analyzed to classify their balance and predict diabetic peripheral neuropathy.

Potential Biases

The study may have bias due to the age difference between the cohorts and the severity of DPN in the diabetic group.

Limitations

The two cohorts were not age-matched, and the diabetic patients were severe cases of DPN, which may affect the generalizability of the results.

Participant Demographics

14 people with diabetes (9 men, 5 women; age range 58-80) and 15 healthy volunteers (14 men, 1 woman; age range 20-55).

Statistical Information

P-Value

p<0.001

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.3390/bioengineering11121241

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