Acute bilateral simultaneous angle closure glaucoma after topiramate administration: a case report
2008
Acute Angle Closure Glaucoma After Topiramate Use
Sample size: 1
publication
Evidence: low
Author Information
Author(s): Chalam Kakarla V, Tillis Tina, Syed Farhana, Agarwal Swati, Brar Vikram S
Primary Institution: Department of Ophthalmology, University of Florida-Jacksonville
Hypothesis
Can topiramate cause acute angle closure glaucoma?
Conclusion
Discontinuing topiramate and starting antiglaucoma therapy normalized intraocular pressures and improved visual acuity.
Supporting Evidence
- Topiramate was associated with severe visual loss in the patient.
- Visual acuity improved significantly after stopping topiramate.
- Intraocular pressures were elevated before treatment.
Takeaway
A woman lost her vision after taking a higher dose of a headache medicine called topiramate, but her vision got better after stopping the medicine.
Methodology
Case report detailing the patient's symptoms, treatment, and outcomes.
Limitations
Only one case is reported, limiting generalizability.
Participant Demographics
34-year-old woman with a history of migraine, hypertension, and hypothyroidism.
Digital Object Identifier (DOI)
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