Progressive Resistance Training and Cancer Testis (PROTRACT) - Efficacy of resistance training on muscle function, morphology and inflammatory profile in testicular cancer patients undergoing chemotherapy: design of a randomized controlled trial
2011

Effects of Resistance Training on Muscle Function in Testicular Cancer Patients

Sample size: 30 publication Evidence: moderate

Author Information

Author(s): Christensen Jesper F, Andersen Jesper L, Adamsen Lis, Lindegaard Birgitte, Mackey Abigail L, Nielsen Rie H, Rørth Mikael, Daugaard Gedske

Primary Institution: Copenhagen University Hospital

Hypothesis

Can high intensity progressive resistance training (HIPRT) mitigate the muscular deterioration caused by chemotherapy in testicular cancer patients?

Conclusion

The study aims to determine if resistance training can improve muscle function and reduce fatigue in testicular cancer patients undergoing chemotherapy.

Supporting Evidence

  • Testicular cancer patients often experience significant muscular fatigue during chemotherapy.
  • Resistance training has been shown to improve muscle strength and function in various populations.
  • The study includes both cancer patients and healthy controls to assess the effects of exercise.

Takeaway

This study is trying to see if exercise can help testicular cancer patients feel stronger and less tired while they get treatment.

Methodology

A randomized controlled trial with 30 testicular cancer patients undergoing chemotherapy, comparing a 9-week HIPRT program to standard care.

Potential Biases

Potential bias in participant selection and the inability to blind participants to their exercise status.

Limitations

The study may not account for all variables affecting muscle function and fatigue in cancer patients.

Participant Demographics

30 testicular cancer patients aged 18-45, and 15 healthy matched control subjects.

Digital Object Identifier (DOI)

10.1186/1471-2407-11-326

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