Cocaine Addiction Treatments to improve Control and reduce Harm (CATCH): New Pharmacological Treatment Options for Crack-Cocaine Dependence in the Netherlands
2011

New Treatments for Crack-Cocaine Dependence in the Netherlands

Sample size: 216 publication Evidence: moderate

Author Information

Author(s): Mascha Nuijten, Peter Blanken, Wim van den Brink, Vincent Hendriks

Primary Institution: Parnassia Addiction Research Centre (PARC, Brijder Addiction Treatment)

Hypothesis

The study investigates the effectiveness of new pharmacological treatments for crack-cocaine dependence.

Conclusion

The CATCH study aims to explore new treatment options for crack-cocaine dependence, focusing on both abstinence and harm minimization.

Supporting Evidence

  • The study is the first in the Netherlands to explore new treatment options for crack-cocaine dependence.
  • Topiramate, modafinil, and dexamphetamine SR are being tested for their effectiveness.
  • The study aims to improve treatment retention and patient satisfaction.

Takeaway

This study is trying to find better ways to help people who are addicted to crack cocaine by testing new medications along with therapy.

Methodology

The study consists of three randomized controlled trials comparing new medications with cognitive behavioral therapy.

Potential Biases

The open-label design may introduce bias as participants are aware of their treatment assignment.

Limitations

Control patients will not receive placebo, and there may be experimenter bias due to the open-label design.

Participant Demographics

Participants are cocaine dependent adults, primarily using crack cocaine, aged 18 and older.

Digital Object Identifier (DOI)

10.1186/1471-244X-11-135

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