Mycobacterium bovis Infection in Cattle in Iran
Author Information
Author(s): Tadayon Keyvan, Mosavari Nader, Sadeghi Fardin, Forbes Ken J.
Primary Institution: University of Aberdeen
Hypothesis
To identify strains of Mycobacterium bovis circulating in Iran.
Conclusion
The study found that the strains of Mycobacterium bovis in Iran were genetically homogeneous despite their wide geographic origins.
Supporting Evidence
- Over 50 million cattle globally are infected with Mycobacterium bovis, causing significant economic loss.
- The study analyzed necropsy specimens from TB-test reactor cattle across 21 Iranian provinces.
- All 132 isolates were confirmed as M. bovis and none were the BCG vaccine strain.
- Spoligotyping identified 8 types, with SB0120 being the most common.
- VNTR typing identified 23 profiles, with low diversity among isolates.
Takeaway
The researchers looked at sick cattle in Iran and found that the bacteria causing their illness were mostly the same type, which is unusual given the large area they came from.
Methodology
The study used region of difference typing, spoligotyping, and variable number tandem repeats typing to analyze 132 M. bovis isolates from cattle.
Limitations
The study was limited by the number of samples that could be exported for analysis.
Participant Demographics
The study focused on Holstein Friesian cattle in Iran.
Digital Object Identifier (DOI)
Want to read the original?
Access the complete publication on the publisher's website