Health-related quality of life of Canadian children and youth prenatally exposed to alcohol
2006

Health-related quality of life of Canadian children and youth prenatally exposed to alcohol

Sample size: 126 publication Evidence: high

Author Information

Author(s): Brenda C Stade, Bonnie Stevens, Wendy J Ungar, Joseph Beyene, Gideon Koren

Primary Institution: St. Michael's Hospital, Toronto, Canada

Hypothesis

To measure the health-related quality of life (HRQL) of Canadian children and youth diagnosed with FASD.

Conclusion

Children and youth with FASD have significantly lower HRQL than children and youth from the general Canadian population.

Supporting Evidence

  • The mean HRQL score of children and youth with FASD was 0.47 compared to a mean score of 0.93 in the general Canadian population.
  • Children demonstrated moderate to severe dysfunction on the attributes of cognition and emotion.
  • The study represents the first research on the topic of FASD and provides a major contribution to new knowledge.

Takeaway

Kids who were exposed to alcohol before they were born have a harder time feeling good about their health compared to other kids.

Methodology

A prospective cross-sectional study design was used with 126 children and youth diagnosed with FASD, aged 8 to 21 years, who completed the Health Utilities Index Mark 3 (HUI3).

Potential Biases

Sampling bias is a possibility as not all families of children with FASD join support groups.

Limitations

The study did not draw from a random sample of children, and individuals residing in institutions were not included.

Participant Demographics

Participants included 54% male and 46% female children, with a mean age of 14.5 years, and varied in cognitive levels and ethnicity.

Statistical Information

P-Value

p < 0.001

Confidence Interval

(95% CI: 0.42 to 0.52)

Statistical Significance

p < 0.001

Digital Object Identifier (DOI)

10.1186/1477-7525-4-81

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