Genetic diversity and multiple introductions of porcine reproductive and respiratory syndrome viruses in Thailand
2011

Genetic Diversity of PRRS Viruses in Thailand

Sample size: 1003 publication Evidence: moderate

Author Information

Author(s): Tun Hein M, Shi Mang, Wong Charles LY, Ayudhya Suparlark NN, Amonsin Alongkorn, Thanawonguwech Roongroje, Leung Frederick CC

Primary Institution: Chulalongkorn University, Bangkok, Thailand

Hypothesis

What is the genetic diversity and origin of porcine reproductive and respiratory syndrome viruses in Thailand?

Conclusion

The study found that PRRS viruses in Thailand originated from multiple introductions, leading to diverse variants co-circulating in major pig-producing provinces.

Supporting Evidence

  • PRRSV has been circulating in Thailand since at least 1989.
  • The study identified multiple independent introductions of both Type 1 and Type 2 PRRSV.
  • Geographic co-circulation of diverse PRRSV variants was observed in three major provinces.

Takeaway

Scientists studied pig viruses in Thailand and found that different types came from various places, making it hard to control them.

Methodology

The study involved isolating viruses from nursery pigs, sequencing their genes, and performing phylogenetic analysis.

Potential Biases

Potential bias due to incomplete sampling and reliance on previously characterized sequences.

Limitations

The study's sampling was limited in both quantity and time span compared to North America.

Participant Demographics

Nursery pigs aged 3-8 weeks from various regions in Thailand.

Digital Object Identifier (DOI)

10.1186/1743-422X-8-164

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