SILVER DIPHOSPHINE COMPLEXES AS ANTIMITOCHONDRIAL AGENTS
Silver Diphosphine Complexes as Antimitochondrial Agents
publication
Author Information
Author(s): Susan J. Berners-Price, Doreen C. Collier, Peter J. Sadler, Rodney E. Sue, David Wilkie
Primary Institution: Griffith University
Hypothesis
The Ag(I) complex inhibits the growth of yeast selectively in non-fermentable media, indicating a primary effect on mitochondrial function.
Conclusion
The Ag(I) complex shows potential as an antimitochondrial agent with the ability to inhibit yeast growth in specific conditions.
Supporting Evidence
- The Ag(I) complex inhibits yeast growth in non-fermentable media.
- Aspirin can largely reverse the antimitochondrial effects of the complex.
Takeaway
This study found that a silver compound can stop yeast from growing by affecting their energy production, but it can be reversed with aspirin.
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