Biosynthesis of Zinc Sulfide/Zinc Oxide Nanocomposite Using Fusarium Oxysporum
Author Information
Author(s): Salaheldin Hosam, Aboelnga Aya, Elsayed Ashraf
Primary Institution: Mansoura University
Hypothesis
Can Fusarium oxysporum be used to biosynthesize zinc sulfide/zinc oxide nanocomposite for various applications?
Conclusion
The study successfully synthesized a ZnO/ZnS nanocomposite that showed significant antibacterial and anticancer activities.
Supporting Evidence
- The ZnO/ZnS nanocomposite showed a dose-dependent cytotoxic effect on breast cancer cells with an IC50 of 197 ± 0.895 µg/mL.
- The nanocomposite removed 87.51% of methylene blue dye.
- The zone of inhibition for MRSA was 35 ± 0.21 mm, indicating strong antibacterial activity.
Takeaway
Scientists used a fungus to make tiny particles that can help kill bacteria and cancer cells and clean up dye from water.
Methodology
The study involved mixing zinc sulfate with fungal cell-free filtrate and incubating it for 96 hours to synthesize the nanocomposite, followed by various characterization techniques.
Limitations
The study does not address the long-term stability of the synthesized nanocomposite in various environments.
Statistical Information
P-Value
p<0.001
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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