Extended Vacuum-assisted Breast Biopsy in Solid Lesions
Author Information
Author(s): Zografos George C, Zagouri Flora, Sergentanis Theodoros N, Koulocheri Dimitra, Nonni Afroditi, Oikonomou Vassiliki, Domeyer Philip, Kotsani Maria, Fotiadis Constantine, Bramis John
Primary Institution: 1st Department of surgery, School of Medicine, Athens University, Greece
Hypothesis
Does the removal of larger volumes of breast tissue during vacuum-assisted breast biopsy result in decreased underestimation of lesions?
Conclusion
The extended protocol seems to totally excise precursor lesions, with minimal underestimation.
Supporting Evidence
- 82.2% of the lesions were benign.
- 14.0% of the lesions were malignancies.
- There was no evidence of underestimation in either protocol.
Takeaway
This study tested a new way to take samples from breast lumps that might help doctors get a better idea of what's going on without missing anything important.
Methodology
107 women underwent vacuum-assisted breast biopsy with two different protocols to compare outcomes.
Potential Biases
The study was conducted at a single center, which may limit generalizability.
Limitations
The sample size is relatively small, and more studies are needed to confirm the findings.
Participant Demographics
Women with a median age of 53 years, undergoing biopsy for non-palpable solid lesions.
Statistical Information
P-Value
p = 0.029
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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