Computer-Aided Diagnosis in Spontaneous Abortion: A Histopathology Dataset and Benchmark for Products of Conception
2024

AI in Diagnosing Miscarriages

Sample size: 5666 publication 10 minutes Evidence: moderate

Author Information

Author(s): Mahmood Tahir, Ullah Zeeshan, Latif Atif, Sultan Binish Arif, Zubair Muhammad, Ullah Zahid, Ansari AbuZar, Zehra Talat, Ahmed Shahzad, Dilshad Naqqash, Chen Dechang

Primary Institution: Atia General Hospital, Karachi, Pakistan

Hypothesis

Can AI techniques improve the accuracy and reliability of histopathological examination of tissue phenotypes in products of conception after spontaneous abortion?

Conclusion

AI techniques can enhance the accuracy and reliability of diagnosing tissue phenotypes in miscarriages compared to traditional methods.

Supporting Evidence

  • AI techniques can reduce subjectivity and inter-observer variability in histopathological examinations.
  • The dataset HistoPoC is the first of its kind focusing on spontaneous abortion in early pregnancy.
  • AI models demonstrated improved diagnostic accuracy compared to traditional methods.
  • The study provides a publicly available resource for further research in histopathology.
  • AI can assist pathologists by providing consistent assessments and reducing human error.

Takeaway

This study shows that using computers can help doctors look at tissue samples from miscarriages more accurately, which can help understand why they happen.

Methodology

The study created a dataset of 5666 annotated histopathology images and evaluated AI techniques against traditional methods for detecting tissue phenotypes.

Potential Biases

The accuracy of AI models relies heavily on the quality of annotations from pathologists, which could introduce biases.

Limitations

The study's findings may not be generalizable due to the dataset being sourced from a single institution and potential biases in expert annotations.

Participant Demographics

The dataset includes tissue samples from 120 patients at Atia Hospital, Karachi, Pakistan.

Digital Object Identifier (DOI)

10.3390/diagnostics14242877

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