Systemic Mastocytosis Associated with Splenic Marginal Zone Lymphoma with Villous Lymphocytes
2011

Case of Systemic Mastocytosis with Splenic Marginal Zone Lymphoma

Sample size: 1 publication Evidence: low

Author Information

Author(s): R. Fernández-Torres, M. M. Verea, A. Álvarez, P. Torres, E. Fonseca

Primary Institution: Complejo Hospitalario Universitario A Coruña

Hypothesis

The association of systemic mastocytosis with splenic marginal zone lymphoma is uncommon and not well established.

Conclusion

This case report highlights a rare association between systemic mastocytosis and splenic marginal zone lymphoma.

Supporting Evidence

  • The patient had systemic mastocytosis diagnosed three years prior to developing lymphoma.
  • Histological examination confirmed the presence of both mast cells and lymphoid cells.
  • The patient received chemotherapy with chlorambucil, leading to some improvement in her condition.

Takeaway

This study talks about a woman who had a skin condition called systemic mastocytosis and later developed a rare type of lymphoma, which is a kind of cancer.

Methodology

The case report includes clinical examination, laboratory tests, and histological evaluations.

Limitations

The findings are based on a single case report, limiting generalizability.

Participant Demographics

A 65-year-old female with a history of urticaria pigmentosa.

Digital Object Identifier (DOI)

10.1155/2011/385074

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