Bacterial Profile and Antibiotic Resistance in Stroke-Associated Pneumonia
Author Information
Author(s): Muacevic Alexander, Adler John R, Mohapatra Smrutisree, Pathi Basanti Kumari, Mohapatra Ipsa, Singh Nipa, Sahoo Jyoti Prakash, Das Narendra Kumar, Pattnaik Dipti
Primary Institution: Kalinga Institute of Medical Sciences, Bhubaneswar, IND
Hypothesis
What is the bacteriological profile and antimicrobial susceptibility patterns of pathogens in patients with stroke-associated pneumonia?
Conclusion
The most common pathogenic bacteria in our study were K. pneumoniae, A. baumannii, P. aeruginosa, E. coli, and S. aureus, with Enterobacterales showing high sensitivity to tigecycline.
Supporting Evidence
- 240 bacterial isolates were found in 181 patients.
- 59 participants had two different isolates in their culture reports.
- A. baumannii was most sensitive to minocycline.
- P. aeruginosa was resistant to tigecycline.
- All S. aureus isolates were sensitive to vancomycin and linezolid.
- Enterobacterales showed high sensitivity to tigecycline.
- Minocycline was the only effective drug against E. meningoseptica.
- Further research is warranted with a larger sample size.
Takeaway
This study looked at sick people who had strokes and got pneumonia, finding out which germs were making them sick and how well antibiotics worked against those germs.
Methodology
This cross-sectional study analyzed bacterial cultures and antimicrobial susceptibility from patients in the neurosurgery ICU who developed pneumonia after stroke.
Potential Biases
Potential bias due to convenience sampling and exclusion of patients who died before sample collection.
Limitations
The study did not analyze recent infection history or the correlation between AST findings and patient outcomes.
Participant Demographics
Median age was 64.50 years, with 26.52% females; most had strokes due to road traffic accidents.
Statistical Information
P-Value
0.05
Confidence Interval
58.74-70.24
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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