Widening of Dynamic Detection Range in Real-Time Angular-Interrogation Surface Plasmon Resonance Biosensor Based on Anisotropic Van Der Waals Heterojunction
2024

Improving Sensitivity and Detection Range in SPR Biosensors

publication Evidence: moderate

Author Information

Author(s): Yu Xiantong, Ouyang Jing, Li Zhao, Shi Chaojun, Wang Longfei, Zhou Jun, Chang Min

Primary Institution: Key Laboratory of Optical Technology and Instrument for Medicine, Ministry of Education, College of Optical-Electrical and Computer Engineering, University of Shanghai for Science and Technology, Shanghai 200093, China

Hypothesis

Can an angular-interrogation SPR biosensor based on black phosphorus and graphene enhance detection sensitivity and dynamic detection range?

Conclusion

The proposed biosensor achieved a maximum detection sensitivity of 258.6 deg/RIU and a dynamic detection range enhancement of 123.1%.

Supporting Evidence

  • The biosensor achieved a maximum detection sensitivity of 258.6 deg/RIU.
  • The dynamic detection range was enhanced by 123.1% using the proposed biosensor.
  • The use of anisotropic 2D material black phosphorus improved both sensitivity and detection range.

Takeaway

This study created a new type of sensor that can detect things better and faster by using special materials called black phosphorus and graphene.

Methodology

The biosensor was designed using a combination of black phosphorus and graphene, and its performance was evaluated through simulations and real-time detection methods.

Limitations

The study primarily focuses on the theoretical design and simulation results, which may not fully represent practical applications.

Digital Object Identifier (DOI)

10.3390/bios14120601

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