Antioxidant and Cancer-Fighting Properties of Acacia nilotica Leaves
Author Information
Author(s): T. Kalaivani, Rajasekaran C., Suthindhiran K., Mathew Lazar
Primary Institution: VIT University
Hypothesis
The study aims to determine the free radical scavenging, cytotoxic, and hemolytic activities of leaves of Acacia nilotica.
Conclusion
The ethanol extract of Acacia nilotica leaves shows significant antioxidant and cytotoxic activities, making it a potential source of anticancer compounds.
Supporting Evidence
- Ethanol extract showed the highest antioxidant activity.
- IC50 values were 53.6 μg/mL for Vero cells and 28.9 μg/mL for Hela cells.
- No hemolytic activity was observed against rat and human erythrocytes.
Takeaway
This study found that a plant called Acacia nilotica can help fight cancer and protect against damage from bad stuff in our bodies.
Methodology
The study used various assays to evaluate antioxidant activity, cytotoxicity on Vero and Hela cell lines, and hemolytic activity.
Limitations
The study did not explore the long-term effects or the specific mechanisms of action of the extracts.
Statistical Information
P-Value
p<0.05
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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