Molecular characterization and phylogenetic study of peste des petits ruminants viruses from North central States of Nigeria
2011

Study of Peste des Petits Ruminants Viruses in Nigeria

Sample size: 33 publication Evidence: moderate

Author Information

Author(s): Luka Pam D, Erume Joseph, Mwiine Frank N, Ayebazibwe Chrisostom, Shamaki David

Primary Institution: Department of Parasitology and Microbiology, School of Veterinary Medicine, Makerere University, Kampala, Uganda

Hypothesis

The study aims to characterize PPR viruses from outbreaks in North Central Nigeria.

Conclusion

PPR is still a problem in Kaduna and Plateau States of Nigeria, and the continued outbreaks are not due to the efficacy of the vaccine.

Supporting Evidence

  • 51.52% of the clinical samples tested positive for PPRV.
  • The strains were genetically closely related to the vaccine strain used in Nigeria.
  • The study is the first to sequence and analyze the F gene from PPR viruses in recent outbreaks.

Takeaway

This study looked at a disease that affects sheep and goats in Nigeria, finding that the viruses are similar to a vaccine strain but the disease is still spreading.

Methodology

Clinical samples were collected from sheep and goats, and PPR viruses were detected using F gene based RT-PCR.

Limitations

The study may not represent all regions of Nigeria as it focused on specific states.

Participant Demographics

Samples were collected from sheep (20) and goats (13) in Kaduna and Plateau States.

Digital Object Identifier (DOI)

10.1186/1746-6148-7-32

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