Methyl 6′-amino-5′-cyano-2′-methyl-2-oxospiro[indoline-3,4′-pyran]-3′-carboxylate
2011
Crystal Structure of a New Compound with Spirooxindole
publication
Evidence: moderate
Author Information
Author(s): Zhu Song-Lei, Liu Ting
Primary Institution: Xuzhou Medical College
Conclusion
The study successfully determined the crystal structure of a new spirooxindole compound, revealing its molecular conformation and hydrogen bonding interactions.
Supporting Evidence
- The new compound was synthesized with a yield of 82%.
- The crystal structure revealed nearly planar conformation of the spiro pyran ring.
- Molecules in the crystal are linked by hydrogen bonds.
Takeaway
Scientists made a new chemical compound and looked at its structure using special techniques. They found out how the atoms are arranged and how they stick together.
Methodology
The compound was synthesized through a reaction of isatin, malononitrile, and methyl 3-oxobutanoate in water, followed by crystallization from ethanol.
Digital Object Identifier (DOI)
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