Satisfaction survey with DNA cards method to collect genetic samples for pharmacogenetics studies
2006

Satisfaction with DNA Cards for Genetic Sample Collection

Sample size: 151 publication Evidence: moderate

Author Information

Author(s): Vidal-Taboada Jose M, Cucala Mercedes, Mas Herrero Sergio, Lafuente Amalia, Cobos Albert

Primary Institution: Pharmacogenomic Unit, RDES SL, Barcelona, Spain

Hypothesis

The study aims to evaluate the implementation of the DNA cards method in a multicentre clinical trial and assess the satisfaction of investigators and patients.

Conclusion

The DNA-cards method was well accepted by investigators and patients, preferred over conventional methods for its ease of use and safety.

Supporting Evidence

  • 100% of blood samples collected were successfully genotyped.
  • Investigators perceived patient satisfaction as very good (60.7%) or good (39.3%).
  • All investigators would recommend using the DNA cards method in future studies.

Takeaway

Researchers found that using special cards to collect blood samples is easier and safer than traditional methods, and both doctors and patients liked it.

Methodology

Blood samples were collected on DNA-cards, and investigators were surveyed about their experiences and perceptions of patient satisfaction.

Limitations

The quantity of DNA recovered from DNA cards was less than that from traditional blood samples, and there were deviations in the collection procedure for some samples.

Participant Demographics

151 patients from 24 participating centres, with 28 investigators involved in the study.

Statistical Information

P-Value

p = 0.001

Confidence Interval

95%CI: 45.7–62.1%

Statistical Significance

p<0.0001

Digital Object Identifier (DOI)

10.1186/1471-2350-7-45

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