Case Report of Metabolic Myopathy and Polyarteritis Nodosa
Author Information
Author(s): Vishwanath Sahana, Abdullah Mishal, Elbalkhi Amro, Ambrus Julian L Jr
Primary Institution: Department of Medicine, SUNY at Buffalo School of Medicine
Hypothesis
Is there a relationship between metabolic myopathy and systemic vasculitis?
Conclusion
The patient's symptoms were likely due to a complex metabolic myopathy, and treatment for both conditions was necessary for improvement.
Supporting Evidence
- The patient had a two-year history of progressive fatigue and exercise intolerance.
- Skin and muscle biopsies confirmed polyarteritis nodosa.
- Biochemical studies indicated defects in mitochondrial function and glycogen storage.
- Treatment for polyarteritis nodosa alone resulted in minimal improvement.
- Dietary changes and supplements led to significant clinical improvement.
Takeaway
A 78-year-old woman had muscle weakness and fatigue due to a rare metabolic condition that made her vasculitis harder to treat, but changing her diet helped her feel better.
Methodology
Case report detailing clinical presentation, laboratory findings, and treatment outcomes.
Limitations
Only one case is reported, limiting generalizability.
Participant Demographics
78-year-old African-American woman.
Digital Object Identifier (DOI)
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